Advances in Biological Solid-State NMR

Proteins and Membrane-Active Peptides

Nonfiction, Science & Nature, Science, Chemistry, Analytic, Biological Sciences, Biochemistry
Cover of the book Advances in Biological Solid-State NMR by Marc Baldus, Michele Auger, Burkhard Bechinger, Valerie Booth, Michael Brown, Myriam Cotten, Tim Cross, Jim Davis, Erick Dufourc, Huub de Groot, Toshimichi Fujiwara, Clemens Glaubitz, Gerhard Grobner, Judith Herzfeld, Mei Hong, Yoshitaka Ishii, Isabelle Marcotte, Beat Meier, Micho Murata, Niels Nielson, Kaoru Nomura, Stanley Opella, Hartmut Oschkinat, Ayyalusamy Ramamoorthy, Bernd Reif, Chad Rienstra, Ichio Shimada, Jenifer Thewalt, Lynmarie Thompson, Robert Tycko, Anne Ulrich, Anthony Watts, Philip Williamson, Gianluigi Veglia, Royal Society of Chemistry
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Author: Marc Baldus, Michele Auger, Burkhard Bechinger, Valerie Booth, Michael Brown, Myriam Cotten, Tim Cross, Jim Davis, Erick Dufourc, Huub de Groot, Toshimichi Fujiwara, Clemens Glaubitz, Gerhard Grobner, Judith Herzfeld, Mei Hong, Yoshitaka Ishii, Isabelle Marcotte, Beat Meier, Micho Murata, Niels Nielson, Kaoru Nomura, Stanley Opella, Hartmut Oschkinat, Ayyalusamy Ramamoorthy, Bernd Reif, Chad Rienstra, Ichio Shimada, Jenifer Thewalt, Lynmarie Thompson, Robert Tycko, Anne Ulrich, Anthony Watts, Philip Williamson, Gianluigi Veglia ISBN: 9781782621195
Publisher: Royal Society of Chemistry Publication: March 17, 2014
Imprint: Royal Society of Chemistry Language: English
Author: Marc Baldus, Michele Auger, Burkhard Bechinger, Valerie Booth, Michael Brown, Myriam Cotten, Tim Cross, Jim Davis, Erick Dufourc, Huub de Groot, Toshimichi Fujiwara, Clemens Glaubitz, Gerhard Grobner, Judith Herzfeld, Mei Hong, Yoshitaka Ishii, Isabelle Marcotte, Beat Meier, Micho Murata, Niels Nielson, Kaoru Nomura, Stanley Opella, Hartmut Oschkinat, Ayyalusamy Ramamoorthy, Bernd Reif, Chad Rienstra, Ichio Shimada, Jenifer Thewalt, Lynmarie Thompson, Robert Tycko, Anne Ulrich, Anthony Watts, Philip Williamson, Gianluigi Veglia
ISBN: 9781782621195
Publisher: Royal Society of Chemistry
Publication: March 17, 2014
Imprint: Royal Society of Chemistry
Language: English

The complexity and heterogeneity of biological systems has posed an immense challenge in recent years. An increasingly important tool for obtaining molecular and atomic scale information on a range of large biological molecules and cellular components is solid-state NMR. This technique can address fascinating problems in structural biology, including the arrangement of supramolecular complexes and fibril formation in relation to molecular folding, misfolding and aggregation.

Advances in Biological Solid-State NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid-state NMR to studies of membrane interactions and molecular motions. A much needed discussion of membrane systems is detailed alongside important developments in in situ analysis.

Topics include applications to biological membranes, membrane active peptides, membrane proteins, protein assemblies and in-cell NMR. This exposition of an invaluable technique will interest those working in a range of related spectroscopic and biological fields. A basic introduction invites those interested to familiarise themselves with the basic mathematical and conceptual foundations of solid-state NMR. A thorough and comprehensive discussion of this promising technique follows, which is essential reading for those working or studying at postgraduate level in this exciting field.

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The complexity and heterogeneity of biological systems has posed an immense challenge in recent years. An increasingly important tool for obtaining molecular and atomic scale information on a range of large biological molecules and cellular components is solid-state NMR. This technique can address fascinating problems in structural biology, including the arrangement of supramolecular complexes and fibril formation in relation to molecular folding, misfolding and aggregation.

Advances in Biological Solid-State NMR brings the reader up to date with chapters from international leaders of this growing field, covering the most recent developments in the methodology and applications of solid-state NMR to studies of membrane interactions and molecular motions. A much needed discussion of membrane systems is detailed alongside important developments in in situ analysis.

Topics include applications to biological membranes, membrane active peptides, membrane proteins, protein assemblies and in-cell NMR. This exposition of an invaluable technique will interest those working in a range of related spectroscopic and biological fields. A basic introduction invites those interested to familiarise themselves with the basic mathematical and conceptual foundations of solid-state NMR. A thorough and comprehensive discussion of this promising technique follows, which is essential reading for those working or studying at postgraduate level in this exciting field.

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