Area of residence and risk of cardiovascular disease and mortality among adults with type 1 diabetes mellitus in Stockholm County

A Swedish cohort study

Master's Thesis from the year 2016 in the subject Medicine - Public Health, grade: B, , course: Department of public health sciences, Epidemiology, language: English, abstract: Cardiovascular disease (CVD) remains a major public health problem in Sweden. Area of residence has been suggested to increase the risk of CVD and CVD specific mortality in the general population but less investigated in adults with type 1 diabetes mellitus. The aim is to deepen knowledge on health inequalities at area level by assessing whether the risk of incident CVD and CVD specific mortality among adults with type 1 diabetes mellitus living in disadvantaged areas differed from those in other areas of Stockholm County. Therefore, a cohort study in which 7544 adults with type 1 diabetes mellitus aged 40-80 years, living in disadvantaged and other areas of Stockholm County in 2006 were followed from 2006-2011. Crude and adjusted hazard ratios for incident CVD and CVD specific mortality were calculated using Cox proportional hazard regression. All models were adjusted for age, gender, education, country of birth, social allowance, disability allowance and disposable income. Results: Adjusted hazard ratios for CVD, stroke, peripheral vascular disease, myocardial infarction and CVD specific mortality were 1.2 (95% CI 0.5-2.0), 1.2 (95% CI 0.6-3.1), 1.0 (95% CI 0.5-2.9), 1.9 (95% CI 1.07-3.6) and 1.3 (95% CI 0.5-4.5) respectively for subjects in disadvantaged areas compared to other areas of Stockholm County.