Biomolecular Interfaces

Interactions, Functions and Drug Design

Nonfiction, Science & Nature, Science, Biological Sciences, Cytology, Biochemistry
Cover of the book Biomolecular Interfaces by Ariel Fernández Stigliano, Springer International Publishing
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Author: Ariel Fernández Stigliano ISBN: 9783319168500
Publisher: Springer International Publishing Publication: April 20, 2015
Imprint: Springer Language: English
Author: Ariel Fernández Stigliano
ISBN: 9783319168500
Publisher: Springer International Publishing
Publication: April 20, 2015
Imprint: Springer
Language: English

The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior.

The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.

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The book focuses on the aqueous interface of biomolecules, a vital yet overlooked area of biophysical research. Most biological phenomena cannot be fully understood at the molecular level without considering interfacial behavior.

The author presents conceptual advances in molecular biophysics that herald the advent of a new discipline, epistructural biology, centered on the interactions of water and bio molecular structures across the interface. The author introduces powerful theoretical and computational resources in order to address fundamental topics such as protein folding, the physico-chemical basis of enzyme catalysis and protein associations. On the basis of this information, a multi-disciplinary approach is used to engineer therapeutic drugs and to allow substantive advances in targeted molecular medicine. This book will be of interest to scientists, students and practitioners in the fields of chemistry, biophysics and biomedical engineering.

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