Biophysics for Therapeutic Protein Development

Nonfiction, Health & Well Being, Medical, Medical Science, Biochemistry, Pharmacology
Cover of the book Biophysics for Therapeutic Protein Development by , Springer New York
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Author: ISBN: 9781461443162
Publisher: Springer New York Publication: February 26, 2013
Imprint: Springer Language: English
Author:
ISBN: 9781461443162
Publisher: Springer New York
Publication: February 26, 2013
Imprint: Springer
Language: English

This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the chapters discuss the applications of these techniques, including case studies, across the product lifecycle from early discovery, where the focus is on identifying targets, and screening for potential drug product candidates, through expression and purification, large scale production, formulation development, lot-to-lot comparability studies, and commercial support including investigations.

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This book can be used to provide insight into this important application of biophysics for those who are planning a career in protein therapeutic development, and for those outside this area who are interested in understanding it better. The initial chapters describe the underlying theory, and strengths and weaknesses of the different techniques commonly used during therapeutic development. The majority of the chapters discuss the applications of these techniques, including case studies, across the product lifecycle from early discovery, where the focus is on identifying targets, and screening for potential drug product candidates, through expression and purification, large scale production, formulation development, lot-to-lot comparability studies, and commercial support including investigations.

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