Author: | Siamak Cyrus Khojasteh, Harvey Wong, Cornelis E.C.A. Hop | ISBN: | 9781441956293 |
Publisher: | Springer New York | Publication: | April 7, 2011 |
Imprint: | Springer | Language: | English |
Author: | Siamak Cyrus Khojasteh, Harvey Wong, Cornelis E.C.A. Hop |
ISBN: | 9781441956293 |
Publisher: | Springer New York |
Publication: | April 7, 2011 |
Imprint: | Springer |
Language: | English |
Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.
Drug Metabolism and Pharmacokinetics Quick Guide covers a number of aspects of drug assessment at drug discovery and development stages, topics such as pharmacokinetics, absorption, metabolism, enzyme kinetics, drug transporters, drug interactions, drug-like properties, assays and in silico calculations. It covers key concepts, with useful tables on physiological parameters (eg. blood flow to organs in x-species, expression and localization of enzymes and transporters), chemical structure, nomenclature, and moieties leading to bioactivation (with examples). Overall it includes a number of key topics useful at the drug discovery stage, which would serve as a quick reference with several examples from the literature to illustrate the concept.