Leucine-Rich Repeat Kinase 2 (LRRK2)

Nonfiction, Health & Well Being, Medical, Specialties, Internal Medicine, Neuroscience, Neurology, Science & Nature, Science
Cover of the book Leucine-Rich Repeat Kinase 2 (LRRK2) by , Springer International Publishing
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Author: ISBN: 9783319499697
Publisher: Springer International Publishing Publication: March 28, 2017
Imprint: Springer Language: English
Author:
ISBN: 9783319499697
Publisher: Springer International Publishing
Publication: March 28, 2017
Imprint: Springer
Language: English

This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.

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This is the first book to assemble the leading researchers in the field of LRRK2 biology and neurology and provide a snapshot of the current state of knowledge, encompassing all major aspects of its function and dysfunction. The contributors are experts in cell biology and physiology, neurobiology, and medicinal chemistry, bringing a multidisciplinary perspective on the gene and its role in disease. The book covers the identification of LRRK2 as a major contributor to the pathogenesis of Parkinson's Disease. It also discusses the current state of the field after a decade of research, putative normal physiological roles of LRRK2, and the various pathways that have been identified in the search for the mechanism(s) of its induction of neurodegeneration.

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