Leucocyte Trafficking

The Role of Fucosyltransferases and Selectins

Nonfiction, Health & Well Being, Medical, Medical Science, Immunology, Physiology
Cover of the book Leucocyte Trafficking by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783662053973
Publisher: Springer Berlin Heidelberg Publication: June 29, 2013
Imprint: Springer Language: English
Author:
ISBN: 9783662053973
Publisher: Springer Berlin Heidelberg
Publication: June 29, 2013
Imprint: Springer
Language: English

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

An essential component of inflammation is the migration of circulating leukocytes from blood into tissues. This process is characterized by a multistep paradigm of sequential cell adhesion and activation events that lead to the extravasation of specific leukocyte subsets to different tissues in health and disease. The first step of leukocyte extravasation, the rolling of leukocytes, is primarily mediated by the interactions of selectins and their ligands. It has recently become evident that fucosyltransferases are crucial for selectin ligand synthesis, inflammation, and skin homing. This book provides an in-depth overview of the mechanisms of leukocyte trafficking and of the molecular mechanisms of selectin/selectin ligand interactions and discusses options for pharmacological intervention to treat inflammatory diseases.

More books from Springer Berlin Heidelberg

Cover of the book Sicherheitsgerichtete Echtzeitsysteme by
Cover of the book Hypospadias Surgery by
Cover of the book Persistent Pollution – Past, Present and Future by
Cover of the book Vertigo - Leitsymptom Schwindel by
Cover of the book Lantibiotics and Related Peptides by
Cover of the book Pädiatrische Differenzialdiagnostik by
Cover of the book Knowledge as a Driver of Regional Growth in the Russian Federation by
Cover of the book Clusters in Nuclei by
Cover of the book Proceedings of the 2nd International Conference on Green Communications and Networks 2012 (GCN 2012): Volume 1 by
Cover of the book Hypercalcemia of Malignancy by
Cover of the book Materials with Complex Behaviour II by
Cover of the book Stochastic Biomathematical Models by
Cover of the book Atlas of Inflammatory Bowel Diseases by
Cover of the book Prüfungstrainer Elektrotechnik by
Cover of the book Physikdidaktik by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy