Neurofibromatosis Type 1

Molecular and Cellular Biology

Nonfiction, Health & Well Being, Medical, Medical Science, Genetics, Specialties, Oncology
Cover of the book Neurofibromatosis Type 1 by , Springer Berlin Heidelberg
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9783642328640
Publisher: Springer Berlin Heidelberg Publication: January 29, 2013
Imprint: Springer Language: English
Author:
ISBN: 9783642328640
Publisher: Springer Berlin Heidelberg
Publication: January 29, 2013
Imprint: Springer
Language: English

Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the NF1 tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome.

Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the NF1 gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Neurofibromatosis type 1 (NF1), caused by mutational inactivation of the NF1 tumour suppressor gene, is one of the most common dominantly inherited human disorders, affecting 1 in 3000 individuals worldwide. This book presents in concise fashion, but as comprehensively as possible, our current state of knowledge on the molecular genetics, molecular biology and cellular biology of this tumour predisposition syndrome.

Written by internationally recognized experts in the field, the 44 chapters that constitute this edited volume provide the reader with a broad overview of the clinical features of the disease, the structure and expression of the NF1 gene, its germ line and somatic mutational spectra and genotype-phenotype relationships, the structure and function of its protein product (neurofibromin), NF1 modifying loci, the molecular pathology of NF1-associated tumours, animal models of the disease, psycho-social aspects and future prospects for therapeutic treatment.

More books from Springer Berlin Heidelberg

Cover of the book Gründung einer Unternehmensberatung by
Cover of the book Microbial Metal Respiration by
Cover of the book Pathways in Applied Immunology by
Cover of the book Reaktortechnik by
Cover of the book The Experimental Investigation of Meaning by
Cover of the book Optical Absorption of Impurities and Defects in Semiconducting Crystals by
Cover of the book Acute Myelogenous Leukemia in Childhood by
Cover of the book Interventional Neuroradiology by
Cover of the book The Chemistry of Superheavy Elements by
Cover of the book Landslide Disaster Mitigation in Three Gorges Reservoir, China by
Cover of the book Biology and Conservation of the European Sturgeon Acipenser sturio L. 1758 by
Cover of the book Environmental Management of Solid Waste by
Cover of the book Cardiovascular Risk in Type 2 Diabetes Mellitus by
Cover of the book The Microeconomic Growth by
Cover of the book Werkstoffe by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy