Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy

Molecular Mechanisms and Clinical Applications

Nonfiction, Health & Well Being, Medical, Medical Science, Pharmacology, Specialties, Oncology
Cover of the book Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy by , Humana Press
View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart
Author: ISBN: 9781603274593
Publisher: Humana Press Publication: January 9, 2009
Imprint: Humana Language: English
Author:
ISBN: 9781603274593
Publisher: Humana Press
Publication: January 9, 2009
Imprint: Humana
Language: English

Cisplatin, the first member of the family of platinum-containing chemotherapeutic agents, was discovered by Barnett Rosenberg in 1965 and approved by the FDA for marketing in 1978. After 30 years of use in the clinic, cisplatin remains a central element of many treatment regimens. Cisplatin is still an irreplaceable component of a regimen that produces high cure rates in even advanced nonseminomatous germ-cell cancers, and is widely used in the treatment of ovarian cancers and other gynecologic cancers, head and neck, and numerous other tumor types. The development of carboplatin has reduced some of the adverse events associated with cisplatin treatment, and the introduction of the DACH platinum compound oxaliplatin has broadened the spectrum of activity of the platinums to include gastro-intestinal cancers, especially colorectal cancer. The clinical importance of this family of drugs continues to drive investigation into how these drugs work and how to improve their efficacy and reduce their toxicity. The papers in this volume were presented in Verona, Italy, during the tenth International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy. The symposium was jointly organized by the Department of Oncology of the Mater Salutis Hospital – Azienda Sanitaria Locale 21 of the Veneto Region – and by the Department of Medicine and Public Health, Section of Pharmacology, the University of Verona. They reflect the vitality of this field and the increasing use of new molecular and cell biologic, genetic, and biochemical tools to identify approaches to further improve their use.

View on Amazon View on AbeBooks View on Kobo View on B.Depository View on eBay View on Walmart

Cisplatin, the first member of the family of platinum-containing chemotherapeutic agents, was discovered by Barnett Rosenberg in 1965 and approved by the FDA for marketing in 1978. After 30 years of use in the clinic, cisplatin remains a central element of many treatment regimens. Cisplatin is still an irreplaceable component of a regimen that produces high cure rates in even advanced nonseminomatous germ-cell cancers, and is widely used in the treatment of ovarian cancers and other gynecologic cancers, head and neck, and numerous other tumor types. The development of carboplatin has reduced some of the adverse events associated with cisplatin treatment, and the introduction of the DACH platinum compound oxaliplatin has broadened the spectrum of activity of the platinums to include gastro-intestinal cancers, especially colorectal cancer. The clinical importance of this family of drugs continues to drive investigation into how these drugs work and how to improve their efficacy and reduce their toxicity. The papers in this volume were presented in Verona, Italy, during the tenth International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy. The symposium was jointly organized by the Department of Oncology of the Mater Salutis Hospital – Azienda Sanitaria Locale 21 of the Veneto Region – and by the Department of Medicine and Public Health, Section of Pharmacology, the University of Verona. They reflect the vitality of this field and the increasing use of new molecular and cell biologic, genetic, and biochemical tools to identify approaches to further improve their use.

More books from Humana Press

Cover of the book Mirror Neuron Systems by
Cover of the book Essential Urology by
Cover of the book Heart Disease and Erectile Dysfunction by
Cover of the book Radiology Sourcebook by
Cover of the book Skeletal Atlas of Child Abuse by
Cover of the book Male Infertility by
Cover of the book Prostate Cancer by
Cover of the book Diagnostic and Therapeutic Procedures in Gastroenterology by
Cover of the book Enzymatic Analysis by
Cover of the book Chronic Pain by
Cover of the book Studies on Cardiovascular Disorders by
Cover of the book Modern Dietary Fat Intakes in Disease Promotion by
Cover of the book Chronic Viral Hepatitis by
Cover of the book Nuclear Reprogramming and Stem Cells by
Cover of the book Modern Therapeutics in Rheumatic Diseases by
We use our own "cookies" and third party cookies to improve services and to see statistical information. By using this website, you agree to our Privacy Policy