Practical Pharmacology for Alzheimer’s Disease

Nonfiction, Health & Well Being, Psychology, Psychiatry, Medical, Specialties, Internal Medicine, Neurology
Cover of the book Practical Pharmacology for Alzheimer’s Disease by Takashi Kudo, Kenneth L. Davis, Rafael Blesa Gonzalez, David George Wilkinson, Springer International Publishing
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Author: Takashi Kudo, Kenneth L. Davis, Rafael Blesa Gonzalez, David George Wilkinson ISBN: 9783319262062
Publisher: Springer International Publishing Publication: February 10, 2016
Imprint: Springer Language: English
Author: Takashi Kudo, Kenneth L. Davis, Rafael Blesa Gonzalez, David George Wilkinson
ISBN: 9783319262062
Publisher: Springer International Publishing
Publication: February 10, 2016
Imprint: Springer
Language: English

In this book, the four leading experts on the ACE inhibitors donepezil, galantamine, and rivastigmine and the NMDA receptor antagonist memantine explain the practical pharmacology of these symptomatic drugs with the aim of providing a sound basis for their clinical use in patients with Alzheimer’s disease. In addition, an introductory chapter considers the basic theory of pharmacology for Alzheimer’s disease and the book closes with an overview of the ways in which symptomatic drugs for dementia are used.

The wide acceptance of the amyloid cascade hypothesis has led to vigorous development of disease-modifying drugs for Alzheimer’s disease, such as amyloid vaccinations and gamma- or beta-secretase inhibitors. The failure of clinical trials of these drugs to yield satisfactory results has, however, meant that for the time being patients continue to be treated only with symptomatic drugs. There is accordingly a need to become more proficient in the use of symptomatic medicines, and it is against the background of this quest that Practical Pharmacology for Alzheimer’s Disease will be of wide interest.

 

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In this book, the four leading experts on the ACE inhibitors donepezil, galantamine, and rivastigmine and the NMDA receptor antagonist memantine explain the practical pharmacology of these symptomatic drugs with the aim of providing a sound basis for their clinical use in patients with Alzheimer’s disease. In addition, an introductory chapter considers the basic theory of pharmacology for Alzheimer’s disease and the book closes with an overview of the ways in which symptomatic drugs for dementia are used.

The wide acceptance of the amyloid cascade hypothesis has led to vigorous development of disease-modifying drugs for Alzheimer’s disease, such as amyloid vaccinations and gamma- or beta-secretase inhibitors. The failure of clinical trials of these drugs to yield satisfactory results has, however, meant that for the time being patients continue to be treated only with symptomatic drugs. There is accordingly a need to become more proficient in the use of symptomatic medicines, and it is against the background of this quest that Practical Pharmacology for Alzheimer’s Disease will be of wide interest.

 

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