The Future of HIV-1 Therapeutics

Resistance Is Futile?

Nonfiction, Health & Well Being, Medical, Medical Science, Microbiology, Pharmacology
Cover of the book The Future of HIV-1 Therapeutics by , Springer International Publishing
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Author: ISBN: 9783319185187
Publisher: Springer International Publishing Publication: April 22, 2015
Imprint: Springer Language: English
Author:
ISBN: 9783319185187
Publisher: Springer International Publishing
Publication: April 22, 2015
Imprint: Springer
Language: English

This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.

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This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike.

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