Resistance to Tyrosine Kinase Inhibitors

Nonfiction, Health & Well Being, Medical, Specialties, Oncology
Cover of the book Resistance to Tyrosine Kinase Inhibitors by , Springer International Publishing
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Author: ISBN: 9783319460918
Publisher: Springer International Publishing Publication: November 7, 2016
Imprint: Springer Language: English
Author:
ISBN: 9783319460918
Publisher: Springer International Publishing
Publication: November 7, 2016
Imprint: Springer
Language: English

The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.

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The volume will serve as a primer on tyrosine kinase signaling and its importance in cancer. The volume will first introduce the common denominators of small-molecule and antibody-derived inhibitors, as well as the general phenomenon of resistance. The volume will then detail resistance to the most commonly used classes of tyrosine kinase inhibitors, and will focus specific chapters on resistance to BCR-ABL1, FLT3, angiokinase family members, and ALK inhibitors.

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